Scientific Publications by Dr Manadan
Peer Reviewed Medical Research Papers
Dr. Augustine M. Manadan is a Chicago-based rheumatologist affiliated with Rush University Medical Center and Cook County Health, specializing in clinical research on autoimmune diseases, including lupus, myositis, tuberculosis, and vasculitis. He has over 60 research works, with significant contributions to analyzing in-hospital mortality and complications in rheumatic patients
1) Manadan AM, Harris C, Schwartz MM, Block JA. The frequency of thrombotic thrombocytopenic purpura in patients with systemic lupus erythematosus undergoing kidney biopsy. J Rheumatol. 2003 Jun;30(6):1227-30.
2) Manadan AM, Block JA, Sequeira W. Mycobacteria tuberculosis peritonitis associated with etanercept therapy. Clin Exp Rheumatol. 2003 Jul-Aug;21(4):526.
3) Mohan AK, Coté TR, Block JA, Manadan AM, Siegel JN, Braun MM. Tuberculosis following the use of etanercept, a tumor necrosis factor inhibitor. Clin Infect Dis. 2004 Aug 1;39(3):295-9.
4) Manadan AM, Block JA. Daily needle aspiration versus surgical lavage for the treatment of bacterial septic arthritis in adults. Am J Ther. 2004 Sep-Oct;11(5):412-5.
5) Manadan AM, Harris C, Block JA. Thrombotic thrombocytopenic purpura in the setting of systemic sclerosis. Semin Arthritis Rheum. 2005 Feb;34(4):683-8.
6) Manadan AM, Sequeira W, Block JA. The treatment of psoriatic arthritis. Am J Ther. 2006 Jan-Feb;13(1):72-9.
7) Manadan AM, James N, Block JA. New therapeutic approaches for spondyloarthritis. Curr Opin Rheumatol. 2007 May;19(3):259-64.
8) Manadan AM, Joyce K, Sequeira W, Block JA. Etanercept therapy in patients with a positive tuberculin skin test. Clin Exp Rheumatol. 2007 Sep-Oct;25(5):743-5.
9) Manadan AM, Block JA. Rheumatoid arthritis: beyond tumor necrosis factor-alpha antagonists, B cell depletion, and T cell blockade. Am J Ther. 2008 Jan-Feb;15(1):53-8.
10) Aggarwal R, Manadan AM, Poliyedath A, Sequeira W, Block JA. Safety of etanercept in patients at high risk for mycobacterial tuberculosis infections. J Rheumatol. 2009 May;36(5):914-7.
11) Ekochin LH, Manadan AM, Aggarwal R, Sequeira W, Block JA. Absence of transaminase elevation during concomitant methotrexate and isoniazid therapy. J Rheumatol. 2009 Sep;36(9):2127.
12) Aggarwal R, Lebiedz-Odrobina D, Sinha A, Manadan A, Case JP. Serum cardiac troponin T, but not troponin I, is elevated in idiopathic inflammatory myopathies. J Rheumatol. 2009 Dec;36(12):2711-4.
13) Mathur T, Manadan AM, Hota B, Block JA. Pseudo-septic hip arthritis as the presenting symptom of ankylosing spondylitis: a case series and review of the literature. Clin Exp Rheumatol. 2010 May-Jun;28(3):416-8.
14) Gan J, Manadan AM, Sequiera W, Block JA. Tuberculosis infections and tumor necrosis factor alpha antagonists. Am J Ther. 2013 Jan;20(1):73-8.
15) Mathur T, Manadan AM, Thiagarajan S, Hota B, Block JA. Corticosteroid Monotherapy Is Usually Insufficient Treatment for Idiopathic Inflammatory Myopathy. Am J Ther. 2015 Sep-Oct;22(5):350-4.
16) Manadan AM, Mushtaq S, Block JA. Radiocarpal and first metatarsophalangeal intraarticular injection site confirmation with fluoroscopy and review of accuracy of intraarticular injections. Am J Ther. 2015 Jan-Feb;22(1):11-3.
17) Dua A, Manadan A. Images in clinical medicine. Heerfordt's syndrome, or uveoparotid fever. N Engl J Med. 2013 Aug 1;369(5):458.
18) Mathur T, Manadan AM, Thiagarajan S, Hota B, Block JA. The utility of serum aldolase in normal creatine kinase dermatomyositis. J Clin Rheumatol. 2014 Jan;20(1):47-8.
19) Dua AB, Manadan AM, Case JP. Adult Onset Still's Disease Presenting with Acute Respiratory Distress Syndrome: Case Report and Review of the Literature. Open Rheumatol J. 2013 Dec 30;7:125-8.
20) Mathur T, Manadan AM, Thiagarajan S, Hota B, Block JA. Serum transaminases are frequently elevated at time of diagnosis of idiopathic inflammatory myopathy and normalize with creatine kinase. J Clin Rheumatol. 2014 Apr;20(3):130-2.
21) Al-Fakhouri A, Manadan A, Gan J, Sreih AG. Central diabetes insipidus as the presenting symptom of granulomatosis with polyangiitis. J Clin Rheumatol. 2014 Apr;20(3):151-4.
22) Raghu P, Manadan AM, Schmukler J, Mathur T, Block JA. Pulse Dose Methylprednisolone Therapy for Adult Idiopathic Inflammatory Myopathy. Am J Ther. 2015 Jul-Aug;22(4):244-7.
23) Manadan AM, Mathur T, Thiagarajan S, Hota B, Block JA. The Authors Respond. J Clin Rheumatol. 2015 Oct;21(7):389.
24) Gandhi NP, Manadan AM, Block JA. Retrospective Study of Patients on Etanercept Therapy for Rheumatic Diseases in Patients With Chronic Hepatitis C Virus. J Clin Rheumatol. 2017 Aug;23(5):252-257.
25) Hassan AS, Rao A, Manadan AM, Block JA. Peripheral Bacterial Septic Arthritis: Review of Diagnosis and Management. J Clin Rheumatol. 2017 Dec;23(8):435-442.
26) Hussain K, Gauto-Mariotti E, Cattoni HM, Arif AW, Richardson C, Manadan A, Yadav N. A Meta-analysis and Systematic Review of Valvular Heart Disease in Systemic Lupus Erythematosus and Its Association With Antiphospholipid Antibodies. J Clin Rheumatol. 2021 Dec 1;27(8):e525-e532.
27) Manadan A, Kambhatla S, Gauto-Mariotti E, Okoli C, Block JA. Rheumatic Diseases Associated With Posterior Reversible Encephalopathy Syndrome. J Clin Rheumatol. 2021 Dec 1;27(8):e391-e394.
28) Edigin E, Eseaton P, Kaul S, Shaka H, Ojemolon PE, Asemota IR, Akuna E, Manadan A. Systemic Sclerosis Is Not Associated With Worse Outcomes of Patients Admitted for Ischemic Stroke: Analysis of the National Inpatient Sample. Cureus. 2020 Jul 12;12(7):e9155.
29) Ojemolon PE, Edigin E, Annapureddy N, Manadan A. A Case of Acute Neck Pain: The Crowned Dens Syndrome. Cureus. 2020 Aug 4;12(8):e9555
30) Edigin E, Ojemolon PE, Eseaton PO, Shaka H, Akuna E, Asemota IR, Manadan A. Rheumatoid Arthritis Patients Have Better Outcomes Than Non-Rheumatoid Arthritis Patients When Hospitalized for Ischemic Stroke: Analysis of the National Inpatient Sample. J Clin Rheumatol. 2022 Jan 1;28(1):e13-e17.
31) Edigin E, Ojemolon PE, Eseaton PO, Shaka H, Akuna E, Asemota IR, Manadan A. Systemic Sclerosis Is Associated With Increased Inpatient Mortality in Patients Admitted for Atrial Fibrillation: Analysis of the National Inpatient Sample. J Clin Rheumatol. 2021 Dec 1;27(8):e477-e481.
32) Edigin E, Shaka H, Eseaton P, Jamal S, Kichloo A, Ojemolon PE, Asemota I, Akuna E, Manadan A. Rheumatoid Arthritis is Not Associated with Increased Inpatient Mortality in Patients Admitted for Acute Coronary Syndrome. Cureus. 2020 Aug 17;12(8):e9799.
33) Manadan A, Edigin E, Attar B. Eosinophilic Esophagitis Occurring After Switching to Ultra-Pasteurized Milk: Coincidence or Unrecognized Etiologic Trigger? Cureus. 2020 Aug 18;12(8):e9828.
34) Edigin E, Hassan AS, Mathur T, Manadan A. The Low Prevalence of Inclusion Body Myositis in an Outpatient Rheumatology Myositis Cohort. Cureus. 2020 Aug 19;12(8):e9873.
35) Edigin E, Akuna E, Asemota I, Eseaton P, Ojemolon PE, Shaka H, Manadan A. Rheumatoid Arthritis Does Not Negatively Impact Outcomes of Patients Admitted for Atrial Fibrillation. Cureus. 2020 Sep 4;12(9):e10241.
36) Manadan AM, Kambhatla S, Gauto-Mariotti E, Okoli C, Block JA. Reasons for Hospitalization and In-Hospital Mortality in Adult Systemic Lupus Erythematosus. ACR Open Rheumatol. 2020 Nov;2(11):683-689.
37) Edigin E, Ojemolon PE, Eseaton PO, Jamal S, Shaka H, Akuna E, Asemota IR, Manadan A. Systemic Sclerosis Is Associated With Increased Inpatient Mortality in Patients Admitted for Acute Coronary Syndrome: Analysis of the National Inpatient Sample. J Clin Rheumatol. 2022 Jan 1;28(1):e110-e117. doi:
38) Patel AR, Desai PV, Banskota SU, Edigin E, Manadan AM. Hemophagocytic Lymphohistiocytosis Hospitalizations in Adults and Its Association With Rheumatologic Diseases: Data From Nationwide Inpatient Sample. J Clin Rheumatol. 2022 Jan 1;28(1):e171-e174.
39) Edigin E, Kaul S, Eseaton PO, Ojemolon PE, Patel A, Manadan A. Psoriasis does not worsen outcomes in patients admitted for ischemic stroke: an analysis of the National Inpatient Sample. J Investig Med. 2021 Jun;69(5):994-998. doi:
10.1136/jim-2020-001678. Epub 2021 Mar 15. PMID: 33723000.
40) Kichloo A, Edigin E, Jamal S, El-Amir Z, Aucar MI, Wani F, Eseaton PO, Annapureddy N, Cabling MG, Manadan AM. Thirty-Day Hospital Readmissions for Acute Gout in the United States: Analysis of the Nationwide Readmission
Database. J Clin Rheumatol. 2022 Mar 1;28(2):e467-e472.
41) Edigin E, Rivera Pavon MM, Eseaton PO, Hernandez C, Manadan A. National trends in psoriasis readmissions: a longitudinal study of the nationwide readmission database from 2010 to 2018. J Eur Acad Dermatol Venereol. 2021
Nov;35(11):e815-e817.
42) Potera J, Kambhatla S, Gauto-Mariotti E, Manadan A. Incidence, mortality, and national costs of hospital admissions for potentially preventable infections in patients with rheumatoid arthritis. Clin Rheumatol. 2021
Dec;40(12):4845-4851.
43) Pavon MR, Sanchez JE, Pescatore J, Edigin E, Richardson C, Manadan A. Reasons for Hospitalization and In-Hospital Mortality in Adults With Dermatomyositis and Polymyositis. J Clin Rheumatol. 2022 Mar 1;28(2):e433-e439.
44) Edigin E, Rivera Pavon MM, Eseaton PO, Manadan A. National trends of psoriasis hospitalizations: a 2-decade longitudinal United States population based study. J Eur Acad Dermatol Venereol. 2021 Dec;35(12):e928-e930.
45) Rivera M, Villafranca A, Khamooshi P, Reyes V, Sanchez J, Manadan A. Reasons for hospitalization and in-hospital mortality for anti-neutrophil cytoplasmic antibody vasculitides: analysis of the National Inpatient Sample. Clin
Rheumatol. 2022 Jan;41(1):159-166.
46) Hassan AS, Edigin E, Patel AR, Manadan A. The Co-existence of Rheumatoid Arthritis and Granulomatosis With Polyangiitis: Two Cases and Review of the Literature. Cureus. 2021 Aug 11;13(8):e17103.
47) Potera J, Palomera Tejeda E, Arora S, Manadan AM. Lupus Enteritis: An Uncommon Presentation of Lupus Flare. Cureus. 2021 Sep 16;13(9):e18030.
48) Benck AR, Manadan A. EJ antibody antisynthetase syndrome. BMJ Case Rep. 2022 Mar 7;15(3):e248318.
49) Whittier M, Bautista Sanchez R, Arora S, Manadan AM. Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome as Risk Factors for Acute Coronary Syndrome in Young Patients: Analysis of the National Inpatient Sample. J Clin Rheumatol. 2022 Apr 1;28(3):143-146.
50) Lopez-Arevalo H, Romero Noboa ME, Joseph D, Edigin E, Arora S, Manadan A. Primary angiitis of the central nervous system and reversible cerebral vasoconstriction syndrome: analysis of the National Inpatient Sample. Clin
Rheumatol. 2022 Aug;41(8):2467-2473. doi: 10.1007/s10067-022-06172-5. Epub 2022 Apr 12.
51) Kwiatkowski A, Shakoor N, Manadan A, Block JA, Khandelwal S. Incorporating interactive workshops into bedside teaching: completion of a multi-modal rheumatology rotation significantly increases internal medicine residents'
competency and comfort with comprehensive knee examinations. BMC Med Educ. 2022 May 10;22(1):355.
52) Potera J, Manadan AM. Reasons for hospitalization and in-hospital mortality in adults with systemic sclerosis: Analysis of the National Inpatient Sample. J Scleroderma Relat Disord. 2022 Oct;7(3):189-196. Epub 2022 May 11.
53) Edigin E, Trang A, Ojemolon PE, Eseaton PO, Shaka H, Kichloo A, Bazuaye EM, Okobia NO, Okobia RI, Sandhu V, Manadan A. Longitudinal trends of systemic lupus erythematous hospitalizations in the United States: a two-decade population-based study. Clin Rheumatol. 2023 Mar;42(3):695-701.
54) Kambhatla S, Vipparthy S, Manadan AM. Rheumatic diseases associated with alveolar hemorrhage: analysis of the national inpatient sample. Clin Rheumatol. 2023 Apr;42(4):1177-1183. doi: 10.1007/s10067-022-06449-9. Epub 2022 Nov 18.
55) Manadan A, Arora S, Whittier M, Edigin E, Kansal P. Patients admitted on weekends have higher in-hospital mortality than those admitted on weekdays: Analysis of national inpatient sample. Am J Med Open. 2022 Nov 22;9:100028.
56) Idolor O, Edigin E, Eseaton PO, Trang A, Kichloo A, Shaka H, Bazuaye EM, Okobia NO, Eboma JE, Uwumiro F, Sandhu VK, Manadan A. Systemic lupus erythematous readmissions have reduced: a 9-year longitudinal study of the
nationwide readmission database. Clin Rheumatol. 2023 Feb;42(2):377-383.
57) Manansala M, Sami F, Arora S, Manadan AM. Reasons for Hospitalization and All-Cause Mortality for Adults with Sarcoidosis. Am J Med Open. 2023 Feb 24;9:100037. doi: 10.1016/j.ajmo.2023.100037.
58) Hino C, Edigin E, Aihie O, Odion J, Eseaton P, Okpujie V, Onobraigho P, Omoike E, Manadan A, Hojjati M. Longitudinal Trends of Hospitalizations for Giant Cell Arteritis: A 21-Year Longitudinal National Population-Based Study. Cureus. 2023 Feb 15;15(2):e35038.
59) Trang A, Kambhatla S, Manadan A. Risk Factors for Respiratory Failure in Patients Hospitalized With Systemic Sclerosis: An Analysis of the National Inpatient Sample. Cureus. 2023 Mar 5;15(3):e35797.
60) Noboa MER, Lopez-Arevalo H, Patel AR, Arora S, Manadan AM. Nationwide analysis of adult hospitalizations with hemophagocytic lymphohistiocytosis and systemic lupus erythematosus. Clin Rheumatol. 2023 Aug;42(8):2091-2095.
61) Idolor O, Edigin E, Hino C, He E, Rao J, Ugoh AC, Onobraigho P, Omoike E, Okpujie V, Ezeafulukwe CJ, Eseaton PO, Manadan A, Downey C. Correction to: Polymyositis/dermatomyositis readmissions: analysis of the nationwide
readmission database. Clin Rheumatol. 2023 Oct;42(10):2921
62) Sami F, Sami SA, Manadan AM, Arora S. Nationwide analysis of neuromyelitis optica in systemic lupus erythematosus and Sjogren's syndrome. Clin Rheumatol. 2024 Jan;43(1):59-65.
63) Sami F, Berg S, Manadan AM, Mycyk MB. Acetaminophen overdose: analysis of 2018 US nationwide emergency database. Intern Emerg Med. 2024 Mar 6.
64) Sami F, Manansala M, Arora S, Manadan AM. Nationwide Analysis of Adult-Onset Still Disease With and Without Hemophagocytic Lymphohistiocytosis. J Clin Rheumatol. 2024 Aug 1;30(5):e125-e128.
65) Manansala M, Castellino J, Arora S, Manadan AM. Nationwide Analysis of Variables Associated With Sarcoid Inpatient Mortality. J Clin Rheumatol. 2024 Nov 11.
66) Romero Noboa ME, Arora S, Kansal P, Manadan AM. Analysis of Takayasu's Arteritis as a Risk Factor for Acute Coronary Syndrome. Am J Med Open. 2025 Mar 15;13:100096.
Publications (Non-PubMed Indexed)
1) Jolly M, Patnaik Asha, O’Brien C, Basu A, Manadan AM., Medical Management of Wrist and Hand Inflammatory Conditions: A Literature Review. Journal of arthroscopy and joint surgery 2018.
2) Parnia Khamooshi, Mavi Rivera Pavon, Cyra Kang-Yoonsun, Viviana Rayes Pinzon, and Augustine Manadan “A Rare Case of Paraneoplastic Dermatomyositis in a Patient with Metastatic Endometrial Cancer" AIMCC